Track 1: Advances in Discovery, Formulation, and Delivery of New Modalities

(T1030-01-01) Development of Physicochemical Profiling Platform for Therapeutic Oligonucleotides

(W1030-01-01) Development of Physicochemical Profiling Platform for Therapeutic Oligonucleotides III Thermodynamic Analysis on Higher-Order Structure of Oligonucleotides

(T1030-01-02) Demonstrating the Excipient Effect In Vitro for Pre-clinical Formulation Analysis

(W1030-01-02) Potential Biomedical Applications of Silver Nanoparticles Synthesized Using Anisotes trisulcus Extract from Saudi Arabia: Antioxidant, Antibacterial, and Anti-Proliferative Properties

(W1030-01-03) Oral Delivery of Remdesivir Analogues: Alternatives for Intravenous Remdesivir with Reduced Potential Drug-Drug Interactions

(T1030-01-03) Stability of Therapeutic Monoclonal Antibodies during Infusion with Elastomeric Pumps Intended for Home-Based Therapy

(W1030-01-04) Preparation and Scale-Up of Liposomal Amphotericin B Formulation and a Comparison with Commercially Available Counterpart, Ambisome®

(T1030-01-05) Flash Nanoprecipitation Permits Self-assembly of Ionizable Lipid Nanoparticles for Nucleic Acid Delivery

(T1030-02-06) A Mechanistic Model of IgG4-RD Identifies High-Potential Therapy Targets

(W1030-02-06) Antibody Synthesis in Cell-Free for High-Throughput Production and Screening

(T1030-02-07) Analytical Method Validation Strategy for Determination of Charge Heterogeneity of Antibody Therapeutics Using Reference Material Comparison as an Alternative to Spiking Studies

(W1030-02-07) Comparative Analyses of Thermal Stability Amplifying Peptide Dendrons and Polysorbates

(W1030-02-08) Optimization of Artificial Colonic Mucus for Drug Diffusion Study

(T1030-02-08) Single Cell Gel Electrophoresis to Detect Genotoxicity of Iminostilbene, a Process Induced Impurity of Carbamazepine

(W1030-02-09) Design and Evaluation of a Cyclic Peptide-Epirubicin Conjugate to Enhance Anticancer Activity and Reduce Cardiac Toxicity

(T1030-02-09) Evaluating the Effects of Differently Charged Linker-Drugs on Pharmacokinetics and Tissue Distribution of Antibody Drug Conjugates

(W1030-02-10) Delivery of Carbonic Anhydrase 9 siRNA by Lipid Nanoparticles

(T1030-02-10) Synthesis a Cationic-Polymer Incorporating Carboxylesterase Active Ester for the Delivery of CRISPR/Cas9 to Ameliorate Hyperlipidemia

(W1030-02-11) Machine Learning Approaches to Analysis of Microscopy Images of Polysorbate Degradation Product Particles

(T1030-02-11) The Importance of Orthogonal Methods for the Determination of the Size Distribution of Lipid Nanoparticles

(W1230-01-01) Development of Physicochemical Profiling Platform for Therapeutic Oligonucleotides IV Evaluation of Compactness of Oligonucleotides for Determining Their Higher-Order Structure

(T1230-01-01) Parallel-Competitive Absorption Metabolism Model for Calculation of Subcutaneous Bioavailability of Monoclonal Antibodies

(W1230-01-02) Impact of Amino Acids as Excipients in Biologic Drug Products Formulation Development

(T1230-01-04) Iontophoretic Transdermal Delivery of a Bioactive Molecule: Comparison of Nanoliposomal Platforms with Passive Delivery

(W1230-01-05) Development of a Marburg Self-amplifying mRNA-Lipid Nanoparticle Vaccine: Differential Effects When Co-formulated with Toll Receptor Agonists

(T1230-01-05) Development of Inhalable Polymeric Nanoemulsions for Delivery of Gene Silencing Therapeutics in Lung Tumors

(T1330-01-01) Development of Physicochemical Profiling Platform for Therapeutic Oligonucleotides II Circular Dichroism Spectroscopy and Nuclear Magnetic Resonance Analysis for Determining Higher-Order Structure

(W1330-01-01) Stabilization of Viruses for Vaccines and Gene Therapy by Spray Drying and Lyophilization

(T1330-01-02) Formulation Development and Characterization of a Marburg Self-amplifying mRNA-Lipid Nanoparticle Vaccine with a Toll-Like Receptor 7 Agonist

(W1330-01-02) Poloxamer 188 and Propylene Glycol Loaded with Novel Pyridine-Based 1,2,4-Triazolo-Tethered Indole Conjugate as Rectal Suppository to Treat Colorectal Cancer

(W1330-01-03) Deciphering the Role of Hydrogel Network Topology in Programmably Degradable Hydrogels

(T1330-01-03) Stain-Free Approach to Determine and Monitor Cell Heath Using Supervised and Unsupervised Image-Based Deep Learning

(T1330-01-04) Predicting the Aggregation Behavior of Liposomes Using Thermal Analysis

(W1330-01-04) Prolonged Ocular Delivery of Sunitinib from Poly (diol-tricarballylate) Injectable Biodegradable Elastomeric Tiny Implant for Diabetic Retinopathy Treatment

(W1330-01-05) Extrapolating the Use of Microfluidic Chips to Formulate Reproducible and Effective Nanoemulsions for Subunit Vaccines: A Paradigm Shift in Manufacturing Emulsion Adjuvants

(T1330-01-05) Optimizing Lipid Nanoparticles (LNPs) Processing for siRNA Delivery by Microfluidics System

(W1430-01-01) Development of Physicochemical Profiling Platform for Therapeutic Oligonucleotides V Biological Function Analysis of Oligodeoxynucleotides

(T1430-01-01) Static Light Scattering Signatures Used to Identify and Minimize Aggregation During Formulation Development

(W1430-01-02) High Concentration Protein Suspensions: A Case Study for Subcutaneous Delivery of Bevacizumab

(T1430-01-03) Val-His-Ser (VHS) N-terminal Leader Sequence and Implications for mAb Subcutaneous Pharmacokinetics

(W1430-01-04) Innovative Device for Concomitant Therapeutic Compound Delivery into the Brain and Neural Recordings - Feasibility Bench and In Vivo Studies

(T1430-01-04) Ionizable Lipid Nanoparticles for Dual siRNA/Chemotherapy Delivery for B-cell ALL Treatment

(W1430-01-05) Characterization of Protein Antigens in Liposomal Vaccines Using Differential Scanning Fluorimetry

(T1530-02-11) Formulation Development and Characterization of a Marburg Self-amplifying mRNA-Lipid Nanoparticle Vaccine with CpG Oligonucleotide

(W1230-01-03) Elastin-Like Polypeptide (ELP) Antibody Fusions Targeting IL-6: Pharmacology and Pharmacokinetics