Description: Mass photometry is a novel bioanalytical technology that provides single-molecule mass measurements of biomolecules in their native state within minutes without the need for labelling, surface immobilization or big sample quantities. Mass photometry is based on interferometric scattering microscopy, measuring single molecules thanks to an unprecedented level of sensitivity. Its ease of use makes mass photometry the perfect tool for rapid assessments of sample purity and homogeneity, structural integrity or macromolecular interactions across biomolecules ranging from differently sized proteins to DNA and even small viruses, such as AAVs.
Learning Objectives:
What mass photometry is and is capabilities.
Mass photometry applications across different fields including PROTACs, proteins, nucleic acids, and viral vectors.