Senior Principal Scientist Bristol-Myers Squibb Company Cambridge, Massachusetts
This case study demonstrates the suitability of using ddPCR method in measuring cellular kinetics of CAR Ts as well show correlation between alternative methods such as flow cytometry and correlation with clinical and efficacy read outs.
Learning Objectives:
have an understanding of ddPCR as an assay format to measure CAR T Cellular Kinetics(CK) and persistence.
understand the implementation of ddPCR assay for persistence monitering in CAR T long term follow up (LTFU) studies.
learn correlation of CAR T persistence and clinical efficacy from a case study.
